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ALCMI launches new CASTLE study to treat lung cancer

The Addario Lung Cancer Medical Institute (ALCMI, voiced as “Alchemy”) today announced the enrollment of the initial subjects into its inaugural clinical trial known as CASTLE, targeting 250 subjects over two years among academic and community medical centers in the United States. CASTLE stands for Collaborative Advanced Stage Tissue Lung Cancer study.

ALCMI is . . . → Read More: ALCMI launches new CASTLE study to treat lung cancer

Targeted Gene Disruption Reveals How Acute Myeloid Leukaemia Develops In Mice

Researchers have described how the most common gene mutation found in acute myeloid leukaemia starts the process of cancer development and how it can cooperate with a well-defined group of other mutations to cause full-blown leukaemia.

The researchers suggest that three critical steps are required to transform normal blood cells into leukaemic ones, . . . → Read More: Targeted Gene Disruption Reveals How Acute Myeloid Leukaemia Develops In Mice

Lupus nephritis ESRD study finds increase in incidence rates among children, African Americans

New research documenting changes in the incidence and outcomes of end-stage renal disease (ESRD) in the U.S. between 1995 and 2006, found a significant increase in incidence rates among patients 5 to 39 years of age and in African Americans. A second related study-the largest pediatric lupus nephritis-associated ESRD study to date-revealed high rates . . . → Read More: Lupus nephritis ESRD study finds increase in incidence rates among children, African Americans

Breast cancer specialists offer new technology for patients to detect early-stage lymphedema

Breast cancer specialists at NewYork-Presbyterian Hospital/Columbia University Medical Center are offering patients new ways to detect early signs of lymphedema, a common side effect of breast cancer surgery that causes painful, debilitating and disfiguring swelling in the arms following removal of lymph nodes.

As many as 30 percent of women who have breast cancer . . . → Read More: Breast cancer specialists offer new technology for patients to detect early-stage lymphedema

New study: Women with early stage breast cancer worry about recurrence

A new study has found that certain types of women with early stage breast cancer are vulnerable to excessive worrying about cancer recurrence. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also indicates that worrying about cancer recurrence can compromise patients’ medical care and quality of life. . . . → Read More: New study: Women with early stage breast cancer worry about recurrence

Proteomics Research Heading Towards Personalized Treatments For Cancer, Diabetes And Inflammatory Diseases

NeoProteomics Inc., a biomarker development and software company, has secured an exclusive option agreement with Case Western Reserve University. The deal has potential to enhance various forms of treatment of cancer, diabetes, and inflammatory diseases.

Proteomics is the scientific next step in vital research of protein structures of biological systems. NeoProteomics, founded in . . . → Read More: Proteomics Research Heading Towards Personalized Treatments For Cancer, Diabetes And Inflammatory Diseases

Now, a one-hour operation to change heart valve!

London: An Indian-origin surgeon-led team in Britain has come up with a one-hour keyhole operation to replace heart valve, a breakthrough which offers hope to cardiac patients too sick to undergo an open-heart surgery.

Vinayak Bapat of Guy’s and St Thomas’ Hospital and his team have developed the procedure, called transcatheter aortic valve implantation . . . → Read More: Now, a one-hour operation to change heart valve!

A Host DNA-Repair Pathway Required For HIV Integration

The human immunodeficiency virus (HIV), the cause of AIDS, makes use of the base excision repair pathway when inserting its DNA into the host-cell genome, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. Crippling . . . → Read More: A Host DNA-Repair Pathway Required For HIV Integration

Carey Anders, MD, UNC Physician-Scientist Receives Grant To Study Breast Cancer Brain Metastases

The American Association for Cancer Research (AACR) has announced that Carey Anders, MD, assistant professor of medicine and a member of UNC Lineberger Comprehensive Cancer Center will receive a Breast Cancer Research Foundation-AACR Grant for Translational Breast Cancer Research. The $181,000 grant will be presented at the organization’s 102nd Annual Meeting, to be held . . . → Read More: Carey Anders, MD, UNC Physician-Scientist Receives Grant To Study Breast Cancer Brain Metastases

Eskimo study suggests fish oils curb diseases

Washington: A study of Alaska’s Yup’ik Eskimos, who consume 20 times more omega-3 fats from fish than most Americans, suggests these oils can prevent obesity-related illness such as diabetes and heart disease, researchers said Friday.

The researchers analyzed data from 330 people living in the Yukon Kuskokwim Delta region of southwest Alaska.

. . . → Read More: Eskimo study suggests fish oils curb diseases

Study develops new approaches for sorting out complexities of cancer cells

New drugs that specifically target the mutated genes responsible for cancer growth have shown great success in extending the lives of patients, with far fewer side effects than conventional anti-cancer therapies. Unfortunately, many patients become resistant to these drugs due to secondary mutations.

Now, a multidisciplinary team of researchers at UCLA has developed . . . → Read More: Study develops new approaches for sorting out complexities of cancer cells

Study identifies unique adult animal stem cells that can turn into neurons

A group of scientists at Marshall University is conducting research that may someday lead to new treatments for repair of the central nervous system.

Dr. Elmer M. Price, who heads the research team and is chairman of Marshall’s Department of Biological Sciences, said his group has identified and analyzed unique adult animal stem cells . . . → Read More: Study identifies unique adult animal stem cells that can turn into neurons

Osteoporotic hip and vertebral fractures have most serious impact on quality of life

A study presented today at the European Congress on Osteoporosis and Osteoarthritis currently taking place in Valencia, Spain has found that the initial quality of life loss following an osteoporotic fracture is substantial, especially with regard to hip and vertebral fractures. The study found differences in quality of life loss between countries after correcting . . . → Read More: Osteoporotic hip and vertebral fractures have most serious impact on quality of life

First evidence of H5N1 transmission between domestic farms and wild birds

Wild migratory birds may indeed play a role in the spread of bird flu, also known as highly pathogenic avian influenza H5N1.

A study by the U.S. Geological Survey, the United Nations Food and Agriculture Organization and the Chinese Academy of Sciences used satellites, outbreak data and genetics to uncover an unknown link . . . → Read More: First evidence of H5N1 transmission between domestic farms and wild birds

Slew of SCH events to mark World TB Day

DOHA: Tuberculosis (TB) claimed at least two lives last year while more than 500 new cases were diagnosed here, according to an expert.

Qatar marked World TB Day (WTD), recently, as a reminder that this very ancient killing disease is still going around silently affecting millions of people every year with about 2 million . . . → Read More: Slew of SCH events to mark World TB Day