Single nucleotide polymorphisms (SNPs) are DNA sequence variations that occur when a single nucleotide in the genome sequence is altered. Prior research suggested an association between SNPs in a gene that encodes aspects of the brain’s gamma-amino butyric acid (GABA)-A receptors (the GABRA2 gene) and alcohol dependence. A study of responses to the aromas of [...]

A molecular test designed to easily diagnose tuberculosis (TB) and detect a drug-resistant form of the bacterium that causes TB can provide much more specific, sensitive and rapid results than currently available TB diagnostics, according to a new study in the New England Journal of Medicine. In a test involving 1,730 patients with suspected drug-sensitive [...]

Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. Researchers from Lund and the UK have now developed a technique that could resolve the situation. In two [...]

A cell devotes a significant amount of effort to maintaining the stability of its genome, preventing the sorts of chromosomal rearrangements characteristic of many cancers. Assays that measure the rate of gross chromosomal rearrangements (GCRs) are needed in order to understand the individual genes and the different pathways that suppress genomic instability. In the September [...]

In the war against antibiotics, bacteria aren’t selfish. According to a new report from Howard Hughes Medical Institute (HHMI) researchers, a handful of resistant pathogens can protect an entire colony. Prevailing wisdom held that antibiotic resistance works only on an individual level: a bacterium acquires a genetic mutation that confers protection against a drug, allowing [...]

When it comes to the mechanics of the human immune system, we are all more alike than previously thought, according to a new study by scientists at Fred Hutchinson Cancer Research Center. This finding has significant implications for developing new ways to detect, diagnose and treat cancer and diseases of the immune system, according to [...]

The existence of chronic Lyme disease is an issue of sharp debate within the medical community. Some health care workers who call themselves “Lyme literate” insist that chronic Lyme disease is frequently diagnosed and treated by primary care physicians. Others, however, including the American Academy of Pediatrics and the Infectious Diseases Society of America, state [...]

Chemotherapy is the best broad defense against cancer recurrence after surgical resection. However, it is difficult to predict which patients will benefit from which regimen of anticancer drugs, if at all. Building on existing knowledge, a study published in the September edition of the Journal of Thoracic Oncology (JTO), analyzed the usefulness of adjuvant chemotherapy [...]

Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology (BAP) has released up-to-the-minute guidelines in the Journal of Psychopharmacology, published by SAGE, to guide psychiatrists and physicians caring for those with sleep problems. BAP members, representative clinicians [...]

New bone analysis shows ancient Nubians consumed tetracycline, most likely in their beer A chemical analysis of the bones of ancient Nubians shows that they were regularly consuming tetracycline, most likely in their beer. The finding is the strongest evidence yet that the art of making antibiotics, which officially dates to the discovery of penicillin [...]

Research links chemical in widely consumed foods to skin cancer The September cover story of the nation’s leading cancer journal, “Cancer Research,” features a new study from The Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer. While the molecular mechanisms of the cancer-promoting effects of capsaicin are [...]

German scientists from Tübingen and Mainz have developed a blood test that can reliably detect gene doping even after 56 days. Scientists at the universities in Tübingen and Mainz have developed a test that can provide conclusive proof of gene doping. “For the first time, a direct method is now available that uses conventional blood [...]

The aluminium content of a range of the most popular brands of infant formulas remains high, and particularly so for a product designed for preterm infants and a soya-based product designed for infants with cow’s milk intolerances and allergies, researchers have found. A study by a team at Keele University in Staffordshire, led by Dr [...]

Cigarette smoke shuts off a key enzyme in airways that regulates the body’s response to inflammation, according to findings from the University of Alabama at Birmingham published online today at Science Express. The UAB researchers say smoke inhibits the enzyme, called Leukotriene A4 Hydrolase (LTA4H), causing it to fail in its job of shutting down [...]

Celsion Corporation (Nasdaq: CLSN), a biotechnology drug development company, announced today that it has been awarded a competitive Phase I Small Business Innovation and Research (SBIR) grant from the National Institutes of Health (NIH), to support the proposal, “New Thermal Sensitive Carboplatin Liposomes for Cancer”. This funding will support the Company’s efforts to develop its [...]